CIRCULATING INFLAMMATORY CYTOKINES INFLUENCING SCHIZOPHRENIA: A MENDELIAN RANDOMIZATION STUDY



A comparative study on the efficacy of 10% hypertonic saline and equal volume of 20% mannitol in the treatment of experimentally induced cerebral edema in adult rats

Abstract Background Hypertonic saline and mannitol are commonly used in the treatment of cerebral edema and elevated intracranial pressure (ICP) at present.In this connection, 10% hypertonic saline (HS) alleviates cerebral edema more effectively than the equal volume of 20% mannitol.However, the exact underlying mechanism for this remains obscure.T

read more

Role of the Combination of Cyclin-Dependent Kinase Inhibitors (CDKI) and Radiotherapy (RT) in the Treatment of Metastatic Breast Cancer (MBC): Advantages and Risks in Clinical Practice

Targeting cell cycle has become the gold standard for metastatic breast cancer (MBC), being Dry Fruits cyclin-dependent kinase inhibitors (CDKIs) cornerstones of its treatment, alongside radiotherapy (RT).To date, no definite evidence regarding safety and efficacy of the combination of CDKIs plus radiotherapy (RT) is currently available.Purpose of

read more

Ancient and modern DNA track temporal and spatial population dynamics in the European fallow deer since the Eemian interglacial

Abstract Anthropogenic factors have impacted the diversity and evolutionary trajectory of various species.This can be through factors such as pressure Dispensers on population size or range, habitat fragmentation, or extensive manipulation and translocation.Here we use time-calibrated data to better understand the pattern and processes of evolution

read more